Are you using the slow ring of Windows update on any of your computers? I have Windows 10 Insider Preview 16232.1000 (rs_prerelease) on this computer.
It must be Windows Defender and the new Microsoft cloud protection because this machine has Kaspersky installed, which has never given me problems with Martin software. When I download from Google Chrome and scan the file with Kaspersky nothing is detected.
Perhaps the new Windows Defender & it's cloud security is much improved, but every time I've used Malwarebytes & Kaspersky, etc. to scan club computers relying on it I've found dozen's if not hundreds of PUP's (Potentially Unwanted Programs) & viruses.